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Toxicity and Safety -Bioavaliabilty and target organs

• Bioavaliabilty and target organs


• Bioavaliabilty


The objective was study the bioavaliabilty of P-MAPA and the target organs for the Mg2 + ions at a single dose of 750 mg/kg


• Pharmacocinetic parameters of single intraperitoneal injection of 750 mg/kg ( Figure 1).


Figure 1




• Target organs of Mg2+ ions


The target organs for the Mg 2+ ions as the follows :


• Liver; pancreas; spleen and stomach



• Lungs, heart; seminal  and kidneys



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